Brain and Cognitive Aging

Amos Pagin

PhD candidate in Psychology at the University of Gothenburg, examining how factors such as education influence late-life brain deterioration and cognitive decline. I work with longitudinal PET and MRI data from the COBRA prospective cohort study, using Bayesian structural equation modeling to track coupled changes in brain structure, neurochemistry, and cognition.

Amos Pagin

About

I work in the Lövdén Lab and the ICON Lab, using longitudinal PET and MRI data from the COBRA prospective cohort study. My dissertation examines whether and how education moderates the relationship between brain change and cognitive decline in healthy older adults. I expect to defend in autumn 2026.

Methodologically, I build large-scale computational pipelines for Bayesian structural equation models, psychometric analyses (CFA, IRT, measurement invariance), and machine learning — often running hundreds of model specifications in batch. I am also developing semla, a Python package for structural equation modeling with Bayesian estimation.

school University of Gothenburg location_on Gothenburg, Sweden

News

Mar 2026

Started development of semla, a Python package for structural equation modeling and latent variable analysis.

Jan 2026

Manuscript on dopamine D2 receptor loss, cognitive decline, and lifestyle factors under revision at Imaging Neuroscience.

Nov 2024

Half-time seminar completed. Department of Psychology, University of Gothenburg.

May 2024

Talk at the COBRA Project Retreat, Max Planck Institute for Human Development, Berlin.

Recent Publications

All Papers arrow_forward
2025 description

Five-Year Associations Among Dopamine D2-Like Receptor Loss, Cognitive Decline, and Lifestyle Factors in Healthy Older Adults

PET imaging from the COBRA study examining five-year associations among dopamine D2-like receptor loss, cognitive decline, and lifestyle factors.

Imaging Neuroscience Under Revision
2023 description

No Moderating Influence of Education on Changes in Hippocampus Volume and Memory

Multi-cohort study testing whether education moderates the link between hippocampal atrophy and memory decline.

Aging Brain Read Paper